Genome Editing Technology in Fishes
Gowhar Iqbal *
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Nahida Quyoom
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Lukram Sushil Singh
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Ad Viral Kumar Ganpatbhai
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Naila M. Bhat
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Shahid Gul
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Mohd Ashraf Malik
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Amritha Mohanty
ICAR-Central Institute of Fisheries Education, Panch Marg, Yari Road, Mumbai-400061, India.
Shakir Ahmad Mir
ICAR-Central Institute of Fisheries Education, Panchmarg, Yari Road, Mumbai-400061, India.
Showkat Ahmad Dar
College of Fisheries Kishanganj Bihar Animal Science University, Patna, India.
*Author to whom correspondence should be addressed.
Abstract
Genome editing and silencing techniques can transform the biology that we understand, diseases affecting fish and other aquatic animals. Gene editing is now being tested in aquaculture, reproduction control, sterility, and disease resistance aspects. More money must be invested in innovative technology to solve these issues in this industry. So gene silencing and genomic DNA editing have the potential significant impact on aquatic animal treatment in the future. Genome editing in fish is an interested part of research that has the potential to revolutionize aquaculture and aid in the understanding of genetic diseases in fish. Genome editing has many applications in editing the genome of fish species for various uses; zinc finger nucleases (ZFNs) were used to experts and follow ethical and regulatory guidelines when conducting fish genome editing disrupt genes in zebrafish (Danio rerio) both somatically and germinally. On the other side, these genetic modification techniques can cause various negative effects through multiple mutations; by that process, it’s challenging to recognise the genetically modified organisms. Genome editing in fish is a complex field requiring specialized knowledge and expertise. It is always advisable to consult with experiments.
Keywords: Gene editing, CRISPR/Cas9, aquaculture, zinc finger nuclease, Transcription Activator-Like Effector Nucleases (TALENs), Fok1